Everyone’s talking about GLP-1s. Fewer people are talking about what happens when you stop taking them.In this episode of FOMO Sapiens, Patrick McGinnis welcomes Geoff Cook, CEO of Noom, for a wide-ranging conversation on weight loss, behavior change, microdosing, and the future of preventative health.
Geoff spent 18 years building The Meet Group, a NASDAQ-listed social entertainment platform he co-founded and led through its $500 million sale, before joining Noom in 2023 to bring the same product-driven mindset to a problem he found more compelling: helping people actually change their health, and keep it changed.
The conversation covers:
- How Noom’s behavior change stack works — from motivation and self-efficacy at the foundation to cognitive behavioral therapy, micro-habit formation, and the Q-microhabit-reward loop designed to hack the brain’s dopamine circuitry
- Why GLP-1s create a “catalytic window” for behavior change: reduced food noise, increased perceived control, and freed-up cognitive capacity that makes it significantly easier to build lasting habits during the medication period
- What the research actually shows about weight regain — studies indicate that real-world GLP-1 users who don’t combine medication with a behavior change program regain all the weight within 18 months of stopping, while those in structured programs maintain results for four or more years
- Why more than 30% of new Noom GLP-1 signups have already been on GLP-1s before — and what that says about the market’s growing understanding of why medication alone isn’t enough
- The case for microdosing: lower price, fewer side effects, and a built-in behavioral commitment that actually drives more engagement with habit formation than higher-dose programs
- How AI is making it possible to synthesize blood work, wearable data, food patterns, and movement data into actionable health insights — something no human clinician could realistically do at scale
- Why Geoff Cook started microdosing himself in October 2024, what it did to his A1C, and how a daily 20-minute run became the keystone habit that compounded into a full morning routine
Patrick and Geoff Cook also get into the cultural shift around GLP-1 stigma, the wild west of telehealth prescribers with no behavior change overlay, and why the most interesting AI story right now isn’t about jobs — it’s about health breakthroughs.